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What to expect in this blog

1. Industrial pain and challenges

  • Thriving but also challenging life science landscape

2. Why can’t you do drug development all alone

  • Independent of the development stage your compound is in, it takes a ‘Tiger Team’ to rocket it to the next step

3. A dynamic and agile strategy to tackle the challenges

  • In 2013, 2 Bridge is Born
  • From NASA’s Tiger Team to drug development: How 2 Bridge aims for the moon in pharma innovation

4. Benefits of working with a Cross-Functional Tiger Team

  • If you are a startup, you gain…
  • If you are an investor, you benefit from…

Thriving, but also challenging life science landscape

The life sciences sector is experiencing rapid growth, with booming R&D efforts driving innovation in drug development. However, small biotech companies face significant challenges in this ever-changing landscape.

  • Limited funding and resources force them to stretch budgets over long, uncertain development cycles, making tough investment decisions based on limited data.
  • The multidisciplinary nature of drug development adds complexity, as small companies struggle to integrate diverse expertise.
  • Competing with larger players is tough, and a single failed trial can be financially devastating, making agility and strategic thinking essential for survival.
  • The rapid pace of innovation, evolving regulatory requirements, and intense competition further complicate this already difficult environment. Drug development is no longer a task for any one group or discipline, but a collective effort that requires agility, adaptability, and strategic foresight.

Independent of the development stage your compound is in, it takes a ‘Tiger Team’ to rocket it to the next step

For every submission, there are:

  • A multitude of scenarios
  • Project & functional budgets
  • Milestones and key deliverables

which need to be carefully balanced according to the project needs.

And each submission needs experts in different functions:

  • Translational sciences
  • Preclinical development
  • CMC
  • Quality
  • Regulatory
  • Clinical & Clinical Operations

All professionals involved in drug development play a critical role in ensuring the drug is discovered, developed, tested, manufactured, and delivered safely and effectively.

In 2013, 2 Bridge was born

After years of working together in a multidisciplinary R&D team, the founding partners of 2 Bridge saw both the challenges and opportunities in the field. This inspired them to create a company with a cross-functional team focused on helping businesses overcome these hurdles and bring science to life.

From NASA’s Tiger Team to drug development – How 2 Bridge aims for the moon in pharma innovation

The term “Tiger Team” was popularized by NASA during the Apollo 13 mission. There, it referred to a cross-functional group of experts from different fields and backgrounds brought together to work on a specific goal or to solve a critical problem. At 2 Bridge, we aim at the moon and propel start-ups forward with our multi-disciplinary subject matter experts (SME). Guided by experienced pharma leaders, they will streamline your compound’s (pre)clinical development, whether it be a small molecule, ASO, ATMP, ADC, peptide, or protein. We strongly believe and testify that the strength of a strong, trusted team that works in a synergistic ‘Tiger Team” manner, could be of great value to other companies engaged in drug development; whether start-ups, academic centers, or even mid-to-large-sized pharmaceutical companies.

When working with a cross-functional team, like a 2 Bridge Tiger Team, you get the option to include the right functional experts at the right time.

If you are a startup, you gain…

  • Rapid access to industry-experienced R&D experts and avoiding obvious pitfalls in the early stages​
  • Flexible support along varying R&D needs resulting in lower costs as compared to full-time hires
  • Seamless integration of 2 Bridge experts into the existing team​
  • Transparent and competitive fee structure allowing focus on R&D activities

If you are an investor, you benefit from…

  • Rapid execution of R&D plans upon funding – no delay in hiring & onboarding​
  • Guidance by independent experts to avoid unnecessary risk-taking and project creeping​
  • Facilitated transition to full-time management and shaping the company for exit options​
  • No dilution of shareholding thereby leveraging early-stage investment​

The science of healthcare product development is our core expertise and building a thriving biotech company around this foundation is our second nature.

Our solutions

Translational Development

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CMC Solutions

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Quality As A Service

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Clinical Development

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Company Building

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